TRPV1 inhibits inflammation through the neuro-immune reflex
10.7644/j.issn.1674-9960.2025.08.010
- VernacularTitle:TRPV1离子通道通过神经-免疫反射抗炎的研究进展
- Author:
Dengcen SONG
1
;
Zijing LIU
;
Cheng CAO
;
Haoyong WANG
Author Information
1. 湖北工业大学,武汉 430068;军事科学院军事医学研究院,北京 100850
- Keywords:
TRPV1;
inflammation;
neuro-immuneregulation;
inflammatory diseases;
therapeutic target
- From:
Military Medical Sciences
2025;49(8):624-628
- CountryChina
- Language:Chinese
-
Abstract:
Transient receptor potential vanilloid 1(TRPV1)ion channel,a non-selective cation channel,not only plays a key role in pain transmission but also serves as a bridge between the nervous system and immune system by regulating neuropeptide release,immune cell activation,and inflammatory signaling pathways.This article summarized its crucial role in inflammatory signal transduction,discussed the interaction mechanism between TRPV1 and the neuro-immune regulatory axis,and explored its potential as a therapeutic target for inflammatory diseases.
