Targeted therapeutic strategies for infectious pneumonia:immunocyte-derived biomimetic nano-drug delivery systems
10.7644/j.issn.1674-9960.2025.08.009
- VernacularTitle:感染性肺炎的靶向治疗新策略:基于免疫细胞的仿生纳米递药系统
- Author:
Hao TIAN
1
;
Qi BA
;
Wei GONG
;
Yuli WANG
;
Yang YANG
;
Chunsheng GAO
;
Meiyan YANG
Author Information
1. 军事科学院军事医学研究院,北京 100850;青岛大学药学院,山东青岛 266000
- Keywords:
biomimetic nano drug delivery system;
infectious pneumonia;
membrane coating;
cell hitchhiking;
pulmonary immunity
- From:
Military Medical Sciences
2025;49(8):617-623
- CountryChina
- Language:Chinese
-
Abstract:
Infectious pneumonia caused by bacteria,viruses,or other pathogenic microorganisms remains a huge threat to human health.Immunocyte-derived biomimetic nano-drug delivery systems can be used for drug delivery by taking advantage of the natural anti-inflammatory effect of immune cells and thus show great potential in lung-targeted therapy.This review begins by introducing different types of immune cells in the lung.The preparation methods of immunocyte-derived biomimetic nano-drug delivery systems and their applications in bacterial pneumonia,viral pneumonia,acute respiratory distress syndrome and cytokine storms are also reviewed.The review is expected to provide data for the targeted therapy of infectious pneumonia.
