Research progress in ultraviolet radiation-induced eye damage and therapeutic drugs
10.7644/j.issn.1674-9960.2025.07.009
- VernacularTitle:紫外线辐射引起的眼部损伤及治疗药物研究进展
- Author:
Jiliang CHEN
1
;
Minghui CUI
;
Yu WU
;
Haobing YU
;
Xiaoyu LIU
;
Bo HU
Author Information
1. 海军特色医学中心,上海 200433;海军军医大学基础医学院,上海 200433
- Keywords:
ultraviolet radiation;
eye injury;
mechanism of action;
therapeutic drugs;
summa
- From:
Military Medical Sciences
2025;49(7):542-547
- CountryChina
- Language:Chinese
-
Abstract:
High intensity ultraviolet radiation exists in special military operation environments such as oceans,plateaus,polar regions and deserts,which is a leading contributor to eye damage and can lead to luminous keratitis,dry eyes,pterygium,cataract and macular degeneration.Ultraviolet radiation can cause acute and chronic injury to eyes by inducing DNA damage,oxidative stress and inflammatory reaction.The commonly used clinical drugs have played a role in relieving symptoms and promoting the repair of ocular tissues,but there are still limitations.The research on targeted therapeutic drugs,proteins and their derived peptides,vitamins and their coenzymes,as well as natural active ingredients of animals and plants has provided new ideas for the development of more effective drugs that can protect eyes from ultraviolet and for medical support to China's army in special environments.Based on the literature currently available,this paper reviews the eye injury caused by ultraviolet radiation and therapeutic drugs in terms of types of eye diseases,injury mechanisms,treatment strategies and drug development.
