Research progress in cell-free biosensors
10.7644/j.issn.1674-9960.2025.02.009
- VernacularTitle:无细胞生物传感器研究进展
- Author:
Cheng ZHANG
1
;
Ningkang YU
;
Chen ZHAO
;
Jingfeng WANG
;
Zhiqiang SHEN
Author Information
1. 军事科学院军事医学研究院,天津 300050
- Keywords:
cell-free biosensors;
recognition elements;
reporting elements;
detection applications
- From:
Military Medical Sciences
2025;49(2):138-143
- CountryChina
- Language:Chinese
-
Abstract:
Cell-free biosensors are detection tools that involve cell-free protein synthesis and consist of recognition elements and reporting elements.These biosensors offer several advantages,such as the ease of construction,a significant specificity and a high sensitivity.By overcoming the limitations associated with cell survival and cell membrane barriers,cell-free biosensors can considerably reduce response times.This article reviewed the recognition and reporting compo-nents of cell-free biosensors,summarizes recent research advancements in their applications to such spheres of public health as environmental monitoring and disease diagnosis,and explores the programmability and logical analysis capabili-ties of these biosensors.Future developments in this field are also predicted.
