Effects of Shugan Jieyu capsules on cardiac function and state of mind of chronic heart failure patients with anxiety and depression
10.7644/j.issn.1674-9960.2025.02.004
- VernacularTitle:舒肝解郁胶囊对慢性心力衰竭伴焦虑抑郁患者心功能和心理状态的影响
- Author:
Bin WANG
1
;
Shuai PANG
;
Shuili L(U)
;
Kuaile CHANG
Author Information
1. 空军军医大学第一附属医院心脏内科,西安 710032
- Keywords:
Shugan Jieyu capsule;
chronic heart failure;
depression;
anxiety;
cardiac function
- From:
Military Medical Sciences
2025;49(2):110-113
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of Shugan Jieyu capsules on the cardiac function and state of mind of chronic heart failure(CHF)patients with anxiety and depression.Methods Ninety-four CHF patients with anxiety and depression were randomly divided into the Shugan Jieyu capsule treatment group and mental therapy control group.Self-rating depression Scale(SDS),self-rating anxiety scale(SAS),left ventricular ejection fraction(LVEF),N-terminal pro-B-type natriuretic peptide(NT-proBNP),the 6-minute walking test(6MWT),hemoglobin(Hb),interleukin-6(IL-6),albumin(ALB)and high-sensitivity c-reactive protein(hs-CRP)were compared between the two groups before and after treatment using t-tests and chi-square tests in order to find out about the efficacy of Shugan Jieyu capsules in CHF patients with anxiety and depression.Results After 8 weeks of treatment,SDS,SAS,NT-proBNP,hs-CRP and IL-6 were all significantly lower,especially in the treatment group,while LVEF,6MWT,Hb and ALB were significantly higher or longer,particularly in the treatment group.Conclusion Shugan Jieyu capsules can effectively alleviate anxiety and depression in CHF patients,improve the cardiac function and nutritional status,and mitigate inflammation.
