Research progress in mechanisms of cannabidiol against drug addiction
10.7644/j.issn.1674-9960.2025.01.010
- VernacularTitle:大麻二酚干预药物成瘾作用机制研究进展
- Author:
Yanlin LI
1
;
Youmin WANG
Author Information
1. 陕西警察学院,西安 710021
- Keywords:
cannabidiol;
drug addiction;
endocannabinoid system;
midbrain limbic dopamine system
- From:
Military Medical Sciences
2025;49(1):61-67
- CountryChina
- Language:Chinese
-
Abstract:
Cannabidiol,a cannabinoid found in the medicinal plant Cannabis,possesses such pharmacological properties as anti-anxiety,antidepressant and sedative effects,so the anti-addiction properties have drawn much attention.This article reviewed recent research progress in the mechanisms of action of cannabidiol in terms of the endocannabinoid system,transient receptor potential vanilloid(TRPV)1 channel,glutamate,dopamie,and serotonin.The role of cannabidiol in treating addiction-related symptoms was summarized in order to provide insights into the potential use of cannabidiol as a treatment for drug addiction.
