Knowledge mapping and visualization analysis of anoikis and cancer research based on Web of Science database
10.7619/jcmp.20253909
- VernacularTitle:基于Web of Science数据库中失巢凋亡与癌症研究的知识图谱可视化分析
- Author:
Huanhuan MA
1
;
Ran DING
;
Junwen WANG
;
Guangying DU
;
Yun ZHANG
;
Qiuchen LU
;
Yingyue HOU
;
Haosong CHEN
;
Hongguan JIAO
Author Information
1. 贵州中医药大学,信息工程学院,550025
- Keywords:
anoikis;
cancer;
drug resistance;
tumor metastasis;
epithelial-mesenchymal transition;
visualization;
tumor microenvironment;
immunotherapy
- From:
Journal of Clinical Medicine in Practice
2025;29(20):20-25,32
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the developmental trends and research hotspots of anoikis in cancer research from 2005 to 2024.Methods Relevant literature was retrieved from the Web of Sci-ence Core Collection.Visualization tools including CiteSpace,VOSviewer and SCImago Graphica were employed to analyze publication volume,countries,institutions,authors,journals,keywords and other bibliometric indicators.Results A total of 2,252 articles were included in this study,showing an overall upward trend in publication volume,with a notable increase after 2012.China and the United States ranked highest in terms of publication volume and citation frequency.Representative institutions included Shanghai Jiao Tong University,Chulalongkorn University and MD Anderson Cancer Center,while a representative scholar was CHANVORACHOTE Pithi.The core journal was Oncogene.Keyword and co-citation analyses revealed that research focused on genetic characteristics,cancer treatment,prognostic prediction and metabolic reprogramming,with core terms including"ex-pression""metastasis"and"anoikis".Conclusion Research interest in the field of anoikis contin-ues to rise,with future directions focusing on drug resistance mechanisms,the tumor microenvironment,immunotherapy,signaling pathways and epithelial-mesenchymal transition(EMT).
