Advances in treatment strategies for drug-eluting stent restenosis of a new classification via optical coherence tomography
- VernacularTitle:基于光学相干断层成像的药物洗脱支架再狭窄新分型治疗策略进展
- Author:
Yuan ZHANG
1
;
Zhen FANG
;
Jing ZHANG
;
Bing XU
;
Gan CAO
;
Zhaoyuan ZHANG
;
Jun JI
Author Information
- Keywords: percutaneous coronary intervention; drug-eluting stent; in-stent restenosis; metal-lic stent platform; optical coherence tomography; intravascular imaging; individualized treatment; ad-vances in strategies
- From: Journal of Clinical Medicine in Practice 2025;29(19):140-144,148
- CountryChina
- Language:Chinese
- Abstract: Catheter-based percutaneous coronary intervention has become a crucial approach for treating obstructive coronary artery disease and is widely applied in clinical practice.Although the new generation of drug-eluting stents(DES)has significantly reduced the incidence of post-procedur-al restenosis and improved long-term clinical outcomes,in-stent restenosis(ISR)remains one of the key challenges affecting the long-term efficacy of percutaneous coronary intervention.Recent studies have demonstrated that DES still have certain inherent limitations.From the metallic stent platform,drug coating to the polymer carrier,each component may exert varying degrees of biological effects on the vascular intima.Optical coherence tomography(OCT),as a high-resolution intravascular imaging technique,has shown significant value in the mechanism research,etiological diagnosis,and clinical classification of ISR.It can clearly identify the tissue composition and morphological characteristics of ISR,providing a precise basis for the formulation of individualized treatment strategies.This review aimed to systematically search the existing literature,comprehensively review the clinical and patho-logical features of ISR after DES implantation,focus on the OCT-based ISR classification system,and summarize the current treatment strategies and latest advances for ISR.
