Research progress of sarcopenia and chronic coronary syndrome in comorbidity mechanisms and their impacts on prognosis
- VernacularTitle:肌少症与慢性冠状动脉综合征共病机制及预后影响的研究进展
- Author:
Yunfan XU
1
;
Zijun YAO
;
Yuli HE
;
Yudong XIA
;
Jun WU
Author Information
- Keywords: sarcopenia; chronic coronary syndromes; geriatric syndrome; skeletal muscle loss; pathogenic mechanism; chronic inflammation; pathophysiological basis; clinical prognosis
- From: Journal of Clinical Medicine in Practice 2025;29(19):136-139
- CountryChina
- Language:Chinese
- Abstract: Sarcopenia is an age-related syndrome characterized by progressive and widespread loss of skeletal muscle mass and/or decline in muscle function.Its incidence increases year by year with aging and is influenced by multiple factors,including genetic background,lifestyle,nutritional status,and chronic diseases.Recent studies have revealed a significant correlation between sarcopenia and chronic coronary syndromes(CCS),not only in terms of the frequency of occurrence but also the se-verity of the conditions.Moreover,sarcopenia and CCS share common pathogenic mechanisms,en-compassing various pathophysiological processes such as chronic inflammation,oxidative stress,apop-tosis,and insulin resistance.This article aimed to review the current research progress on comorbidity relationship between sarcopenia and CCS,explore their shared pathophysiological basis,and discuss their impacts on clinical prognosis.
