Chinese and international organoid research trends:a comparative bibliometric analysis based on CiteSpace
- VernacularTitle:基于CiteSpace的国内外类器官研究热点比较与趋势分析
- Author:
Zhihua CAO
1
;
Tengjia HUANG
;
Yixin LIU
;
Xi CAO
;
Ziying LI
;
Sheng LI
;
Lihua QIN
Author Information
- Keywords: organoid; research hotspots; biomechanics; translational medicine; stem cells; drug screening; regenerative medicine; bibliometrics
- From: Journal of Clinical Medicine in Practice 2025;29(16):14-19,27
- CountryChina
- Language:Chinese
- Abstract: Objective To integrate multi-source heterogeneous literature data from China Na-tional Knowledge Infrastructure(CNKI),Wanfang,VIP,and Web of Science(WoS)databases u-sing bibliometric methods,and to comparatively analyze the differences in knowledge structure charac-teristics and evolutionary pathways of organoid research between China and foreign countries.Meth-ods CiteSpace software was employed to conduct a visual atlas analysis of the publication volume,countries,institutions,authors,and keywords of 1,118 Chinese literatures and 10,871 English lit-eratures.Results China ranked the second globally in terms of publication volume(accounting for 22.09％),but exhibited low centrality in international collaboration networks.The density of the do-mestic institutional collaboration network was 0.003,indicating a relatively loose structure,with Fudan University leading domestic output with 15 Chinese papers.Keyword emergence analysis revealed that"organ-on-a-chip"and"biomechanics"have emerged as new hotspots since 2024.Conclusion It is recommended to establish an interdisciplinary collaborative innovation alliance to focus on break-throughs in the translational directions of organ-on-a-chip and biomechanics,thereby addressing the imbalance between"scale and quality"in China's organoid research.
