Review in mechanisms of action and intervention strategies of gut microenvironment in childhood neurodevelopmental disorders
- VernacularTitle:肠道微环境在儿童神经发育障碍中的作用机制及干预策略研究综述
- Author:
Yuxuan LIU
1
;
Lei LEI
Author Information
- Keywords: gut microbiota; childhood; neurodevelopmental disorders; fecal microbiota trans-plantation; microbiome-gut-brain axis; probiotics; imbalance of immune regulation; dysbacteriosis
- From: Journal of Clinical Medicine in Practice 2025;29(12):142-148
- CountryChina
- Language:Chinese
- Abstract: Childhood neurodevelopmental disorders represent a significant public health concern that has garnered considerable attention.In recent years,the impact of the gut microenvironment on childhood neurodevelopmental disorders has emerged as a research hotspot.This article reviewed the current research status regarding the relationship between the gut microenvironment and childhood neu-rodevelopmental disorders,encompassing the early connections between the gut microenvironment and the nervous system,the concept of the microbiome-gut-brain axis,the mechanisms of action of the gut microenvironment in childhood neurodevelopmental disorders,clinical diagnosis,and intervention strategies.Furthermore,it provided insights into future research directions,emphasizing the impor-tance of deeply exploring mechanisms of action,developing precise intervention strategies,and strengthening multidisciplinary collaboration,with the aim of providing new ideas and evidence for the prevention and treatment of childhood neurodevelopmental disorders.
