Construction and validation of a risk prediction model for in-hospital death after successful resuscitation in patients with cardiac arrest
10.7619/jcmp.20246109
- VernacularTitle:心脏骤停患者复苏成功后院内死亡的风险预测模型构建及验证
- Author:
Yu LI
1
;
Zhen CHEN
;
Xin GUO
;
Yifan LIANG
;
Jueyan WANG
;
Jinlei LI
;
Xianting YANG
;
Fen AI
Author Information
1. 江汉大学医学部,湖北武汉,430113
- Keywords:
cardiac arrest;
sudden cardiac death;
cardiopulmonary resuscitation;
return of spontaneous circulation;
in-hospital death;
nomogram model;
sinus rhythm;
norepinephrine
- From:
Journal of Clinical Medicine in Practice
2025;29(11):26-32,41
- CountryChina
- Language:Chinese
-
Abstract:
Objective To construct and validate a risk prediction model for in-hospital death af-ter successful resuscitation in patients with cardiac arrest.Methods A retrospective study was con-ducted on 295 patients with cardiac arrest who successfully restored spontaneous circulation after car-diopulmonary resuscitation and were further treated in hospital.The patients were divided into training and validation sets using K-fold cross-validation and then grouped and compared based on whether in-hospital death occurred.A binary Logistic regression analysis was used to screen risk prediction fac-tors,and a nomogram prediction model was constructed.The model performance was evaluated and validated in the training and validation sets,respectively.Results The results of the multivariate Logistic regression analysis showed that hospitalization duration(OR=1.180;95％CI,1.080 to 1.280;P＜0.001),norepinephrine dose(OR=0.980;95％CI,0.970 to 0.990;P=0.002),ini-tial respiratory rate after resuscitation(OR=1.090;95％CI,1.030 to 1.150;P=0.004),and sinus rhythm recovery after resuscitation(OR=4.280;95％CI,1.670 to 10.980;P=0.003)were inde-pendent influencing factors for in-hospital death.A nomogram model was constructed based on these in-dependent influencing factors,and it was verified that the model had good discrimination,calibration,applicability,and rationality.Conclusion The influencing factors for in-hospital death after successful resuscitation in patients with cardiac arrest include hospitalization duration,norepinephrine dose,initial respiratory rate after resuscitation,and sinus rhythm recovery after resuscitation.The nomo-gram model constructed based on these factors can provide a reference for clinical decision-making.
