A case of acute kidney injury caused by unexplained rhabdomyolysis misdiagnosed as liver failure
- VernacularTitle:误诊肝衰竭的不明原因横纹肌溶解所致的急性肾损伤1例
- Author:
Lanfen PENG
1
;
Bolin ZHAN
;
Wenmin YANG
;
Yuan YANG
;
Yan WANG
;
Jialing SUN
;
Xiaozhou ZHOU
Author Information
- Keywords: rhabdomyolysis; acute kidney injury; myoglobinuria; etiology analysis; clinical syndrome; creatine kinase; delayed diagnosis; pathophysiological mechanism
- From: Journal of Clinical Medicine in Practice 2025;29(10):146-148
- CountryChina
- Language:Chinese
- Abstract: Rhabdomyolysis is a clinical syndrome characterized by damage to the integrity of skel-etal muscle cell membranes,massive release of intracellular contents(such as myoglobin,creatine ki-nase,and electrolytes)into the bloodstream,thereby triggering systemic pathophysiological responses.Its most common and severe complication is acute kidney injury,primarily resulting from the combined effects of myoglobin deposition in renal tubules and renal ischemia.Due to lack of specific early clini-cal manifestations,patients are often misdiagnosed or experience delayed treatment,which can lead to exacerbation of the condition and even life-threatening consequences.This article reports a case of a patient who presented with unexplained rhabdomyolysis at onset and subsequently developed acute kid-ney injury during the course of the disease.A systematic analysis and discussion of the potential etiolo-gy are conducted based on the patient's clinical features and laboratory test results.
