Immunotherapy of γδT cells in hepatocellular carcinoma:current status and perspectives
- VernacularTitle:γδT细胞在肝细胞癌免疫治疗中的现状与展望
- Author:
Lingling CAO
1
;
Xiaocai MEI
;
Qian CHEN
;
Jian ZHANG
Author Information
- Keywords: γδT cells; hepatocellular carcinoma; antitumour immunity; immunotherapy; bio-markers; therapeutic targets; genetic variation; tumor microenvironment
- From: Journal of Clinical Medicine in Practice 2025;29(7):131-137
- CountryChina
- Language:Chinese
- Abstract: The hepatocellular carcinoma(HCC)poses a serious threat to human health.The main target of one of the immunotherapeutic approaches is γδT cells.γδT cells as one of the subpop-ulations of T lymphocytes can directly recognize and target HCC cells,making them a potential target for immunotherapy.In this paper,we discussed the biological properties of γδ T cells and their dual roles within HCC cells and therapeutic strategies,and provide an overview on the research of γδT cell therapy for HCC.
