Research progress in immune disorders and glucocorticoid therapy in severe viral pneumonia
- VernacularTitle:重症病毒性肺炎免疫紊乱与糖皮质激素治疗研究进展
- Author:
Linyong SHI
1
;
Xuecong YU
;
Qianru DU
;
Yaoyong WANG
Author Information
- Keywords: severe viral pneumonia; immune dysfunction; glucocorticoids; immunomodulatory agents; immune profiling; pathogenesis; respiratory viruses; immune disorder
- From: Journal of Clinical Medicine in Practice 2025;29(6):139-142,148
- CountryChina
- Language:Chinese
- Abstract: Immune dysfunction plays a pivotal role in the pathogenesis and progression of severe viral pneumonia.Both hyperactivated immune responses and immunosuppressive states may adversely affect clinical outcomes.Glucocorticoids,widely utilized as immunomodulatory agents,hold significant therapeutic value in managing this condition.Elucidating the intricate mechanisms underlying immune dysregulation in these patients,accurately assessing individualized immune profiles,and optimizing glucocorticoid regimens alongside other immunomodulatory interventions are critical to improving clini-cal success rates.This review synthesized current progress in research on immune disorders and glu-cocorticoid therapy in severe viral pneumonia,providing theoretical foundations for clinical practice to enhance patient prognosis.
