Research progress on genetic factors related to lung function
- VernacularTitle:肺功能相关遗传因素的研究进展
- Author:
Panying LI
1
;
Xiaofeng ZHANG
;
Jianyun YIN
;
Xiaowei REN
;
Jing YANG
;
Qian NI
Author Information
- Keywords: lung function; genetics; environment; whole genome
- From: Journal of Clinical Medicine in Practice 2025;29(3):133-137,143
- CountryChina
- Language:Chinese
- Abstract: Lung function serves as a clinical indicator reflecting respiratory system function,ai-ding in the diagnosis and monitoring of pulmonary diseases.Both genetic and environmental factors ex-ert significant influences on lung function.A comprehensive understanding of the role of genetic factors in lung function is crucial for gaining deeper insights into the regulatory mechanisms of lung function.In recent years,with the application of advanced technologies such as genome-wide association stud-ies,whole-exome sequencing,whole-genome sequencing,and epigenome-wide association studies,numerous genetic loci related to lung function have been identified.This review aimed to summarize the current research progress in genetics related to lung function,providing a reference for subsequent in-depth exploration of the pathological and physiological mechanisms affecting lung function.
