Impact of permissive low-calorie feeding on nutritional status and prognosis in intensive care unit patients with severe pneumonia
- VernacularTitle:容许性低热量喂养对重症监护病房重症肺炎患者营养状态和预后的影响
- Author:
Le ZHANG
1
;
Hanqiu LIU
;
Yuping ZHANG
Author Information
- Keywords: permissive low-calorie feeding; intensive care unit; severe pneumonia; hospital-ization; nutritional status
- From: Journal of Clinical Medicine in Practice 2025;29(3):94-98
- CountryChina
- Language:Chinese
- Abstract: Objective To investigate the impact of permissive low-calorie feeding on nutritional status and prognosis in patients with severe pneumonia in the intensive care unit(ICU).Methods A total of 100 patients with severe pneumonia in ICU were selected and divided into low-calorie feeding group and adequate feeding group using a random number table method,with 50 patients in each group.The low-calorie feeding group received permissive low-calorie feeding,and the adequate feeding group received adequate feeding,both conducting for a duration of one week.Clinical indicators,nutri-tional indicators,inflammatory indicators,respiratory function indicators,and intestinal mucosal barrier function indicators were compared between the two groups before treatment and one week after treatment.The incidence of hospital-acquired pneumonia(HAP)and complications(including septic shock,pul-monary edema,bronchiectasis,etc.)were also compared between the two groups.Results The fever clearance time,mechanical ventilation time,and ICU stay duration were shorter in the low-calo-rie feeding group compared to the adequate feeding group(P＜0.05).There was no statistically sig-nificant difference in 28-day mortality between the two groups(P＞0.05).After treatment,there were no statistically significant differences in serum total protein(TP),prealbumin(PA),hemoglobin(HGB),and albumin(ALB)levels between the low-calorie feeding group and the adequate feeding group(P＞0.05).The levels of procalcitonin(PCT)and high-sensitivity C-reactive protein(hs-CRP)were lower in the low-calorie feeding group compared to the adequate feeding group(P＜0.05).The oxygenation index,ventilation volume,mean arterial pressure,and central arterial pressure were lower in the low-calorie feeding group compared to the adequate feeding group(P＜0.05).The levels of D-lactic acid and diamine oxidase(DAO)were also lower in the low-calorie feeding group compared to the adequate feeding group(P＜0.05).The incidence of HAP and complica-tions was 4.00％and 10.00％in the low-calorie feeding group and 14.00％and 18.00％in the adequate feeding group,respectively,with no statistically significant differences(P＞0.05).Con-clusion Permissive low-calorie feeding has a positive effect on the early recovery of ICU patients with severe pneumonia,which can improve respiratory function and intestinal mucosal barrier func-tion and reduce inflammatory levels.
