Research progress on hyperoxia-induced brain injury in preterm infants
- VernacularTitle:早产儿高氧导致脑损伤的研究进展
- Author:
Ziyi ZENG
1
;
Meicen ZHOU
;
Hua WANG
Author Information
- Keywords: hyperoxia; brain injury; bronchopulmonary dysplasia; preterm infant; animal ex-periments; neonate
- From: Journal of Clinical Medicine in Practice 2025;29(1):136-143
- CountryChina
- Language:Chinese
- Abstract: With the advances of technology in neonatal intensive care unit(NICU),oxygen therapy in the resuscitation and treatment of preterm infants is widely applied,which significantly im-proves their survival rates.However,complications associated with hyperoxia,such as early onset pre-term encephalopathy(EOP),retinopathy of prematurity(ROP),and bronchopulmonary dysplasia(BPD),severely affect the quality of life of surviving preterm infants.This article reviewed the current clinical and animal experimental research on hyperoxia-induced brain injury,clarifying the potential manifestations and mechanisms of neurological damage related to hyperoxia in preterm infants.The find-ings provide a theoretical basis for safe oxygen use decisions in clinical practice for preterm infants.
