Safety and effectiveness of endovascular stenting for symptomatic intracranial arterial stenosis
- VernacularTitle:血管内支架置入术治疗症状性颅内动脉狭窄的安全性及有效性研究
- Author:
Guirong YIN
1
;
Qiliang GU
;
Guixia FU
Author Information
- Keywords: symptomatic intracranial arterial stenosis; stent placement; cerebral blood perfu-sion; neurological function; adverse reactions
- From: Journal of Clinical Medicine in Practice 2025;29(1):98-101
- CountryChina
- Language:Chinese
- Abstract: Objective To investigate the safety and effectiveness of endovascular stent place-ment in the treatment of symptomatic intracranial arterial stenosis(sICAS).Methods A total of 100 patients with sICAS were selected and randomly divided into control group and study group using a random number table method,with 50 patients in each group.The control group received standard pharmacological therapy,while the study group underwent endovascular stent placement.The in-tracranial artery stenosis rate,neurological function[assessed by the National Institutes of Health Stroke Scale(NIHSS)score],activities of daily living[assessed by the Activities of Daily Living(ADL)score],and cerebral blood perfusion indicators[peak systolic velocity(PSV)and pulsatility index at the stenotic segment]before and 14 days after treatment were compared between the two groups.Additionally,the incidence of adverse reactions was compared.Results After treatment,the intracranial artery stenosis rates were lower in both groups compared to before treatment,and the study group was lower than the control group(P＜0.05).The NIHSS scores were lower in both groups after treatment compared to before treatment,and the study group was lower than the control group(P＜0.05).After treatment,the ADL scores were higher in both groups compared to before,and the study group was higher than the control group(P＜0.05).After treatment,both PSV and the pulsatility index were lower in both groups compared to before treatment,and they were lower in the study group than in the control group(P＜0.05).The incidence of adverse reactions was lower in the study group than in the control group(P＜0.05).Conclusion Endovascular stent placement is effective in treatment of patients with sICAS,and it can significantly reduce the intracranial artery stenosis rate,improve neurological function and activities of daily living,demonstrating high safety.
