ANTHELMINTIC EFFICACY OF COMPOUNDED FIPRONIL DROPS AGAINST PARASITIC TICKS IN DOGS
10.3969/j.issn.1005-0507.2025.03.006
- VernacularTitle:复方非泼罗尼滴剂对犬体寄生蜱的驱杀效果评价
- Author:
Shi-Jie LI
1
;
Guo-Qing CHEN
;
Yang-Ying CHENG
;
Yan ZHANG
;
Meng-Meng DENG
;
Wei JI
;
Deng-Long XIE
;
Xun SUO
Author Information
1. 浙江海正动物保健品有限公司,杭州 311401
- Keywords:
Compound Fipronil Spot-on Solutions;
Tick;
Safety;
Clinical therapeutic effect
- From:
Acta Parasitologica et Medica Entomologica Sinica
2025;32(3):167-173
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of Compound Fipronil Spot-on Solution in repelling canine ticks.Methods A total of 140 dogs infested with ticks were randomly selected from regions in southern and northern China and assigned to four groups:southern test drug group,southern control drug group,northern test drug group,and northern control drug group.Each group comprised 35 dogs.Each dog was administered the prescribed dose.The number of ticks was counted on days 1,7,14,21,and 28 following the administration.The negative conversion and average reduction rates of the tick population were then subjected to statistical analyse.Results The mean efficacy of the test drug was 100%in both the southern and northern cohorts,28 days post-treatment.The control drug showed comparable efficacy,reaching a mean reduction of 100%in both regions by the same time point.No additional clinical manifestations or adverse events were observed across all treated dogs.Conclusions Compound Fipronil Spot-on Solutions effectively treats and prevents ticks in dogs in different regions of China.A single dose remains effective for up to 28 days,thus providing a convenient,effective solution.
