SIMULTANEOUS DETECTION OF SFTSV RNA FROM SERUM,URINE AND THROAT SWAB SAMPLES FROM A PATIENT IN ANHUI PROVINCE,CHINA
10.3969/j.issn.1005-0507.2021.04.006
- VernacularTitle:从安徽1名患者血清、尿液和咽拭子样本中检测到发热伴血小板减少综合征病毒核酸
- Author:
Le-Le AI
1
;
Dan HU
;
Chang-Qiang ZHU
;
Na YUE
;
Qiu-Wei WANG
;
Fu-Qiang YE
;
Heng LYU
;
Ming YUE
;
Wei-Long TAN
Author Information
1. 东部战区疾病预防控制中心,江苏 南京 210002
- Keywords:
SFTSV;
Body fluids;
Laboratory examination;
Sequencing analysis
- From:
Acta Parasitologica et Medica Entomologica Sinica
2021;28(4):237-242,270
- CountryChina
- Language:Chinese
-
Abstract:
Severe fever with Thrombocytopenia Syndrome(SFTS)is an emerging epidemic disease caused by a novel SFTS bunyavirus(SFTSV).It is widely spread in central and northeast of China,particularly in rural and hilly areas,posing a great threat to public health.Here we presented a SFTS case in Anhui Province with clinical symptoms of fever,leukopenia and thrombocytopenia which SFTSV was detected in serum,urine and throat swab samples by RT-qPCR.Two gene fragments of viral complementary DNA were obtained by RT-PCR and sequenced from the patient's body fluids.Phylogenetic analysis indicated that the sequences obtained were closely related to those from patients in other epidemic areas of China.To our knowledge,it was the first report on the simultaneous detection of SFTSV RNA from serum,throat swabs and urine in the same patient,which suggest to be alert to the possible ways of SFTSV transmission other than tick bite.
