Current status and progress of mechanical thrombectomy for intracranial distal medium vessel occlusion
10.3969/j.issn.1008-794X.2025.12.019
- VernacularTitle:颅内远端中等血管闭塞机械取栓治疗现状及进展
- Author:
Kun CHENG
1
;
Xing ZHONG
;
Weiwei KE
;
Gang DENG
Author Information
1. 210009 江苏南京 东南大学医学院、东南大学附属中大医院介入与血管外科
- Keywords:
stroke;
distal medium vessel occlusion;
mechanical thrombectomy
- From:
Journal of Interventional Radiology
2025;34(12):1389-1394
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,with the rapid development of mechanical thrombectomy(MT)for acute large vessel occlusion,an increasing number of clinical studies begin to focus on the acute distal medium vessel occlusion(DMVO).This article systematically reviews the existing literature,summarizes the definition and classification of DMVO,the advance in MT,the imaging evaluation methods,and the clinical application of emerging technologies.Currently,the definition of DMVO is mostly based on vascular anatomical features and clinical functional deficits,the etiology of DMVO can be classified as primary and secondary.Due to the small diameter and tortuous running course of distal medium vessels,individualized treatment strategies are often required for patients with DMVO.This review focuses on the efficacy and safety of the therapeutic techniques,including direct thrombectomy,aspiration thrombectomy,stent retriever thrombectomy,and bridging therapy,in treating DMVO,besides,this review also discusses the role of imaging methods,including non-enhanced CT(NCCT),CT perfusion(CTP),CT angiography(CTA),and MRI in the patient screening and treatment decision-making.Meanwhile,the emergence of novel small-scale thrombectomy devices and techniques offers new possibilities for improving recanalization rates and reducing complication risks.Overall,although preliminary studies suggest that MT has promising clinical benefits for the treatment of DMVO,the available evidence remains limited.High-quality randomized controlled trials are urgently needed to further formulate the optimal treatment strategies and promote the precision interventional therapy.
