Application of ProGlide vascular stitching device in catheter-directed thrombolysis for patients with arterial thrombosis of lower limb:analysis of its safety and efficacy
10.3969/j.issn.1008-794X.2025.12.015
- VernacularTitle:ProGlide血管缝合器在下肢动脉置管溶栓治疗中的安全性和有效性研究
- Author:
Tao LIU
1
;
Suiyuan SHANG
;
Bo SUN
;
Jicun ZHANG
;
Jiefeng ZHANG
;
Jihong LIU
Author Information
1. 261000 山东潍坊 潍坊市人民医院血管外科
- Keywords:
ProGlide vascular stitching device;
arterial thrombolysis;
puncture point;
complication
- From:
Journal of Interventional Radiology
2025;34(12):1364-1368
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the safety and effectiveness of ProGlide vascular stitching device in catheter-directed thrombolysis for patients with thrombosis of lower limb arteries.Methods The patients with arterial thrombosis of lower extremity,who received catheter-directed thrombolysis at the Department of Vascular Surgery of Weifang People's Hospital of China from January 2020 to December 2023,were collected for this study.In performing the vascular interventional surgery,a 6-Fr femoral artery sheath was used to accomplish the catheter-directed thrombolysis in all patients.When the catheter-directed thrombolysis was ended,ProGlide vascular stitching device was used to suture the femoral artery puncture point,or the femoral artery puncture point was oppressed with a finger.The hemostatic success rate and the incidence of relevant complications were compared between the two groups.Results A total of 156 patients who received catheter-directed thrombolysis of lower extremity were enrolled in this study.Of the 156 patients,ProGlide vascular stitching device was used to suture the femoral artery puncture point in 80(ProGlide device group)and finger-oppression was adopted in 76(finger-oppression group).Compared with finger-oppression group,in ProGlide device group the hemostatic success rate was obviously higher(96.25％vs.80.3％,P=0.002).Nine patients in finger-oppression group(11.8％)and 2 patients in ProGlide device group(2.5％)developed puncture site hematoma or pseudoaneurysm(P=0.023).Five patients in finger-oppression group(6.6％)had to receive surgical operation to repair the femoral artery,and one patient in ProGlide device group(1.25％)developed ProGlide device-related femoral artery occlusion.Adverse events occurred in 15 patients(19.7％)of finger-oppression group and 3 patients(3.75％)of ProGlide device group(P=0.002).Conclusion ProGlide vascular stitching device can be safely used in patients with arterial thrombosis of lower extremity receiving catheter-directed thrombolysis.This device carries high success rate for suturing the femoral artery puncture point,thus,the incidence of hematoma at the puncture site can be reduced.
