The efficacy and safety of endovascular treatment for tandem and non-tandem vertebrobasilar artery occlusions
10.3969/j.issn.1008-794X.2025.12.013
- VernacularTitle:血管内治疗对椎基底动脉串联闭塞和非串联闭塞的作用
- Author:
Yujia LIAO
1
;
Junzhe LI
Author Information
1. 110001 辽宁沈阳 中国医科大学附属第四医院导管室
- Keywords:
vertebrobasilar artery tandem occlusion;
acute ischemic stroke;
endovascular treatment;
recanalization of blood vessel;
mortality;
symptomatic intracranial hemorrhage
- From:
Journal of Interventional Radiology
2025;34(12):1353-1359
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effectiveness and safety of endovascular treatment(EVT)for acute tandem vertebrobasilar artery occlusions(tVBAO).Methods A computerized retrieval of academic papers concerning the EVT treatment for acute tVBAO from the databases of PubMed,Cochrane Library,CNKI,Wanfang database was conducted.The retrieval time period was from the establishment of the database to September 30,2024.The outcome indexes included successful recanalization of responsible vessels(mTICI≥grade 2b),good clinical prognosis in 90 days(mRS:0-2 points),symptomatic intracranial hemorrhage(sICH)and mortality.The clinical outcomes were compared between the tVBAO patients and non-tVBAO patients.A random effects model was used to calculate the pooled risk ratio(RR).Results Nine eligible academic papers with 1 725 patients were finally included in this study,including 314 tVBAO patients and 1 411 non-tVBAO patients.There were no significant differences in the successful recanalization of responsible blood vessels(RR=0.99,95％CI:0.94-1.04,P=0.67),good clinical prognosis at 90 days(RR=0.99,95％CI:0.74-1.34,P=0.96),and mortality(RR=1.18,95％CI:0.88-1.59,P=0.28)between the tVBAO group and the non-tVBAO group.The sICH in the tVBAO group was significantly higher than that in the non-tVBAO group(RR=1.76,95％CI:1.12-2.78,P=0.02).Conclusion After EVT,there are no significant differences in the successful recanalization of responsible blood vessels,90d good clinical prognosis,and mortality rate between tVBAO patients and non-tVBAO patients.However,after EVT the risk of sICH in tVBAO patients is significantly higher than that in the non-tBBAO patients.
