Ultrasound-guided microwave ablation combined with ethanol injection for cystic-solid thyroid nodules:a meta analysis
10.3969/j.issn.1008-794X.2025.11.013
- VernacularTitle:超声引导下微波消融联合无水乙醇注射治疗甲状腺囊实性结节Meta分析
- Author:
Qian ZHAO
1
;
Yijiang YU
;
Qiaofeng LUO
Author Information
1. 223001 江苏淮安 淮安市中医院内分泌科
- Keywords:
thyroid nodule;
microwave ablation;
percutaneous ethanol injection;
meta-analysis
- From:
Journal of Interventional Radiology
2025;34(11):1235-1240
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinical efficacy and safety of ultrasound-guided microwave ablation(MWA)combined with percutaneous ethanol injection(PEI)and MWA alone for the treatment of cystic-solid thyroid nodules.Methods A computerized retrieval of academic papers concerning the randomized controlled trials(RCT)on the comparison of the effectiveness and safety between MWA combined with PEI(combination group)and MWA alone(simple MWA group)for cystic-solid thyroid nodules from the databases of PubMed,China National Knowledge Internet(CNKI),Wanfang Database,etc.was conducted.The quality of the enrolled articles was assessed according to the Newcastle-Ottawa scale(NOS)score.Results A total of six articles including 458 patients were finally included in this meta-analysis.Meta-analysis showed that the volume reduction rate of cystic-solid thyroid nodules in the combination group was higher than that of the simple MWA group(P＜0.05).No statistically significant differences in the complication incidences of hoarseness and fever existed between the two groups(both P＞0.05),but the complication incidences of bleeding and neck pain in the combination group were lower than those in the simple MWA group(both P＜0.05).Conclusion In treating cystic-solid thyroid nodules,MWA combined with PEI is superior to MWA alone in the curative effect and clinical safety.
