Advances in percutaneous ablation for pulmonary oligometastases from colorectal cancer
10.3969/j.issn.1008-794X.2025.09.020
- VernacularTitle:结直肠癌肺寡转移瘤经皮消融治疗进展
- Author:
Mingyuan HOU
1
;
Yibing LI
;
Zhenhua DU
;
Zhilong WANG
;
Taiyang ZUO
Author Information
1. 261053 山东潍坊 山东第二医科大学医学影像学院;曲阜市中医院医学影像科
- Keywords:
colorectal cancer;
pulmonary metastasis;
oligometastatic;
percutaneous ablation
- From:
Journal of Interventional Radiology
2025;34(9):1023-1029
- CountryChina
- Language:Chinese
-
Abstract:
Colorectal cancer(CRC)is one of the most common malignant tumors worldwide,metastasizing most commonly to the liver and lung.Local treatment of pulmonary oligometastases from CRC has an important position in the therapeutic course of the disease,sometimes local therapy is the key to achieve a disease-free state.Surgery is the preferred treatment for pulmonary oligometastases from CRC,but some patients are unable to undergo surgery due to physical conditions or lesion's anatomical location limitations.Because of its minimally-invasive manipulation,repeatable adoption,maximum preservation of lung parenchyma and lung function,and the potential to cure new or recurrent lung metastases,percutaneous ablation therapy has emerged as an important surgical alternative,and its clinical application has been increasing in recent years.Percutaneous ablation techniques mainly include radiofrequency ablation(RFA),microwave ablation(MWA),and cryoablation(CA).RFA produces thermal effect through high-frequency electrical current,and it is easy to operate and applicable for a wide range of treatments.MW A uses efficient microwave heating technique and its energy distribution is uniform,suitable for larger lesions.Through repeated freeze-thaw cycles CA destroys tumor tissues,which is particularly suitable for the lesions near important structures.Besides,percutaneous ablation combined with surgery,medication,etc.can be used for the treatment of pulmonary oligometastases from CRC,this kind of combination therapy has synergistic effect to enhance the curative efficacy.This paper aims to make a comprehensive review about the importance of treating pulmonary oligometastases from CRC,the efficacy,prognosis,and influencing factors of various percutaneous ablation techniques,and the application progress of ablation combined with other therapies.
