Early endovascular treatment for cerebral infarction caused by intracranial atherosclerosis or cardioembolism:a comparative study
10.3969/j.issn.1008-794X.2025.09.003
- VernacularTitle:颅内动脉粥样硬化和心源性栓塞脑梗死早期血管内治疗的对比研究
- Author:
Youqing XU
1
;
Haichen SHEN
;
Xiangjun XU
;
Junfeng XU
;
Ke YANG
;
Xianhui DING
;
Xianjun HUANG
Author Information
1. 241001 安徽芜湖 皖南医学院弋矶山医院神经内科
- Keywords:
intracranial atherosclerosis;
cardioembolism;
large vessel occlusion;
endovascular treatment;
therapeutic efficacy;
safety
- From:
Journal of Interventional Radiology
2025;34(9):931-934
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinical efficacy and safety of early endovascular treatment(EVT)for the stroke patients caused by large vessel occlusion(LVO)due to intracranial atherosclerosis(ICAS)or due to cardioembolism(CE).Methods The clinical data of 488 patients with acute anterior circulation LVO stroke,who received early endovascular treatment at the Yijishan Hospital of Wannan Medical College of China from October 2015 to December 2023,were retrospectively analyzed.According to the cause of disease,the patients were divided into ICAS group(n=108)and CE group(n=380).The clinical data,mainly including the proportion of patients having a good prognosis at 90 days after operation(modified Rankin Scale score ≤2 points),the incidence of symptomatic intracranial cerebral hemorrhage(sICH),and the mortality of patients at 90 days after operation.Multivariate logistic regression analysis was used to analyze the factors influencing patient's prognosis.Results Of the 488 patients,29(5.9％)developed postoperative sICH,242(49.6％)achieved a good prognosis at 90 days after the operation,and 91(18.6％)died.The above outcomes in the ICAS group were one,66,and 11 patients respectively,which in the CE group were 28,176,and 80 respectively,and the differences between the two groups were statistically significant(all P＜0.05).Multivariate logistic regression analysis indicated that good prognosis at 90 days after the operation(OR=0.962,95％CI:0.404-2.288,P=0.930)and the postoperative 90-day mortality(OR=1.379,95％CI:0.436-4.362,P=0.584)were not the factors influencing prognosis,while the postoperative sICH(OR=19.132,95％CI:1.332-274.791,P=0.030)was the factor influencing prognosis.Conclusion In CE group,the incidence of sICH and the postoperative 90-day mortality are higher,while in ICAS group,the postoperative 90-day good prognosis rate is higher.The postoperative sICH is the factor influencing prognosis.
