Mechanical thrombectomy versus standard medication therapy for acute vertebrobasilar arterial occlusive mild stroke:comparison of clinical effect
10.3969/j.issn.1008-794X.2025.08.015
- VernacularTitle:机械取栓对比标准药物治疗急性椎基底动脉闭塞性轻型卒中临床效果
- Author:
Caiyun YANG
1
;
Jianjun LI
;
Shijie NA
Author Information
1. 239300 安徽天长 天长市人民医院神经内科
- Keywords:
mild stroke;
vertebrobasilar artery;
postcirculatory stroke;
mechanical thrombectomy;
endovascular treatment
- From:
Journal of Interventional Radiology
2025;34(8):882-887
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compared the clinical efficacy of mechanical thrombectomy and standard medication therapy in the treatment of patients with acute vertebrobasilar arterial occlusive mild stroke.Methods The clinical data of a total of 105 patients with acute vertebrobasilar arterial occlusive mild stroke,who were admitted to the Tianchang Municipal People's Hospital of China from January 2019 to December 2023,were retrospectively analyzed.According to the therapeutic scheme,the patients were divided into mechanical thrombectomy group(n=37)and standard medication therapy group(n=68).Based on the age,sex,onset-to-admission interval,National Institutes of Health Stroke Scale(NIHSS)score,the propensity score matching with 1∶1 ratio was conducted for the patients.The clinical outcome was compared between the two groups.Results After propensity score matching,a total of 68 patients were enrolled in this study,with 34 patients in each group.The mean age was(68.3±11.9)years,45 patients(66.2％)were male,and the median NIHSS score was 2 points.No statistically significant differences in the baseline data existed between the two groups(all P＞0.05).In the standard medication therapy group,10 patients(29.4％)developed early deterioration of the neurological functions,and the median NIHSS score was 12 points,all the 10 patients received salvage mechanical thrombectomy,and 9 patients achieved a successful recanalization.Follow-up check at 90 days after surgery showed that modified Rankin scale(mRS)score of 0-1 point was seen in one patient,and 0-2 points was seen in 2 patients.The proportions of 90-day mRS score of 0-1 point and 0-2 points in the mechanical thrombectomy group were remarkably higher than those in the standard medical therapy group(67.6％vs.41.2％and 85.3％vs.61.8％respectively,both P＜0.05).No statistically significant differences in the hemorrhagic transformation rate(5.9％vs.8.8％)and 90-day mortality(5.9％vs.14.7％)existed between the two groups(both P＞0.05).Conclusion Compared with standard medication therapy,the mechanical thrombectomy can improve the clinical prognosis of patients with acute vertebrobasilar arterial occlusive mild stroke and will not increase the incidence of surgical complications.Therefore,acute vertebrobasilar occlusive mild stroke may be a good indication for mechanical thrombectomy treatment.
