AcoStream mechanical thrombectomy for the treatment of acute high-risk pulmonary embolism:its clinical efficacy and risk factors
10.3969/j.issn.1008-794X.2025.08.006
- VernacularTitle:AcoStream血栓抽吸手术治疗急性高危肺栓塞的疗效及其风险因素
- Author:
Yanqing ZHANG
1
;
Xuezhen XU
Author Information
1. 264003 山东烟台 滨州医学院第二临床医学院
- Keywords:
pulmonary embolism;
thrombectomy;
AcoStream mechanical thrombectomy
- From:
Journal of Interventional Radiology
2025;34(8):834-839
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the efficacy and safety of AcoStream mechanical thrombectomy(AMT)system in treating high risk acute pulmonary embolism(APE),and to analyze the risk factors associated with postoperative recurrence of pulmonary embolism(PE).Methods A total of 137 patients with APE,who were admitted to Bingzhou Medical University Hospital Yantai Affiliated hospital from January 2018 to April 2023,were collected.The patients were divided into AMT group(receiving AMT treatment,n=76)and catheter-directed thrombolysis group(CDT group,n=61).The preoperative risk,surgical core indicators,perioperative and follow-up results,and incidence of adverse events were compared between the two groups.One month after treatment,the risk factors for PE recurrence in the AMT group were analyzed.Results Compared with the CDT group,in the AMT group the preoperative risk stratification of pulmonary embolism was higher,the patients were older,the cardiac function grade was higher,the intraoperative used urokinase dose was less,and the postoperative hospital stay was shorter;the differences in the above indexes between the two groups were statistically significant(all P＜0.05).During follow-up period of one month,the difference in the recurrence of pulmonary embolism between the two groups was statistically significant(P=0.026).Logistic regression analysis revealed that pre-operative NT-proBNP was the risk factor for PE recurrence at one month after AMT treatment(OR=1.001,95％CI:1.000-1.001).Conclusion AMT technique carries high efficacy for removing thrombus in different pulmonary artery segments,which is suitable for the treatment of APE.While reducing the bleeding amount,AMT technique will not increase the time spent for operation,besides,it has excellent advantages in improving the right heart function and in ensuring clinical safety.
