The clinical application of NOVA stent in the treatment of symptomatic middle cerebral artery atherosclerotic stenosis
10.3969/j.issn.1008-794X.2025.05.010
- VernacularTitle:NOVA支架在症状性大脑中动脉粥样硬化性狭窄患者中的临床应用
- Author:
Jing LUO
1
;
Xiangrong SUN
;
Jichong XU
;
Shuo YAN
;
Chun FANG
;
Lin MA
Author Information
1. 637000 四川南充 川北医学院临床医学系;什邡市人民医院神经内科
- Keywords:
middle cerebral artery stenosis;
intracranial artery atherosclerosis;
endovascular therapy;
NOVA stent;
stroke
- From:
Journal of Interventional Radiology
2025;34(5):496-499
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical safety and efficacy of NOVA stent implantation in the treatment of symptomatic middle cerebral artery(MCA)atherosclerotic stenosis.Methods The clinical data,including surgical results,perioperative complications,imaging manifestations and follow-up findings,of 21 patients with severe MCA atherosclerotic stenosis,who received NOVA stent implantation at the Affiliated Tongji Hospital of Tongji University of China from November 2021 to February 2023,were retrospectively analyzed.Results Successful NOVA stent implantation was accomplished in all the 21 patients.The residual stenosis was less than 30％,with no bleeding complications.After stent implantation,the median stenosis ratio of responsible vessels decreased from preoperative 85.04％to postoperative 5.95％,the difference was statistically significant(P＜0.01).During the follow-up period of 10-14 months,one patient(4.76％)developed in-stent restenosis,one patient developed transient ischemic attack(TIA),and one patient developed posterior circulation cerebral infarction.No cerebral hemorrhage or death occurred.After treatment,the clinical symptoms were stable in 16 patients(76.19％),improved in 4 patients(19.04％),and worsened in one patient(4.76％).Conclusion For the treatment of patients with symptomatic MCA atherosclerotic stenosis,NOVA stent implantation is clinically safe and effective.However,multicenter randomized controlled studies with larger sample size and longer follow-up period need to be conducted before its curative efficacy can be further validated.
