The prediction value of the early efficacy of hepatic arterial infusion chemotherapy in patients with stageⅡ-Ⅲ hepatocellular carcinoma
10.3969/j.issn.1008-794X.2025.05.009
- VernacularTitle:肝动脉灌注化疗对Ⅱ-Ⅲ期肝癌早期疗效的预测价值
- Author:
Wenjuan YANG
1
;
Meier WU
;
Keqin ZHANG
;
Haibin YU
;
Jinming LIU
;
Bing OUYANG
;
Wenying WANG
;
Ling WEI
;
Shu XIONG
Author Information
1. 330000 江西南昌 南昌市第九医院肝脏肿瘤科
- Keywords:
hepatic arterial infusion chemotherapy;
stage Ⅱ-Ⅲ hepatocellular carcinoma;
early efficacy
- From:
Journal of Interventional Radiology
2025;34(5):493-495
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the prediction value of the early efficacy of hepatic arterial infusion chemotherapy(HAIC)in treating stage Ⅱ-Ⅲ hepatocellular carcinoma(HCC).Methods The clinical data of 81 patients with stage Ⅱ-Ⅲ HCC,who received at least 3 times of HAIC at the Nanchang Municipal Central Hospital of China from November 2021 to March 2024,were retrospectively analyzed.CT or MRI was used to compare patient's local tumor response after each treatment cycle.Based on modified Response Evaluation Criteria in Solid Tumors(mRECIST),the curative effects of patients after receiving the first,the second,and the last HAIC treatment were compared between each other.The prediction value of the early efficacy of HAIC in treating patients with stage Ⅱ-Ⅲ HCC was analyzed.Results In the 67 patients,the efficacy of the last time HAIC was equal or similar to that of the first time HAIC,and in the remaining 14 patients the efficacy of the last time HAIC was different from that of the first time HAIC,with an efficacy prediction rate of 82.72％.The efficacy of the last time HAIC was equal or similar to that of the second time HAIC in 71 patients,and in the remaining 10 patients the efficacy of the last time HAIC was different from that of the second time HAIC,with an efficacy prediction rate of 87.65％.Conclusion In treating stage Ⅱ-Ⅲ HCC with HAIC,the early efficacy can be used to predict the final efficacy after completion of the total treatment course.
