Current status and progress of transarterial interventional treatment for liver metastases from neuroendocrine tumors
10.3969/j.issn.1008-794X.2025.05.002
- VernacularTitle:神经内分泌肿瘤肝转移经动脉介入治疗现状及进展
- Author:
Siyi LUO
1
;
Peng LIU
;
Xu ZHU
Author Information
1. 100142 北京 北京大学肿瘤医院介入治疗科
- Keywords:
neuroendocrine neoplasm;
liver metastasis;
transarterial interventional treatment;
combination therapy
- From:
Journal of Interventional Radiology
2025;34(5):456-460
- CountryChina
- Language:Chinese
-
Abstract:
Clinically,neuroendocrine liver metastasis(NELM)is not uncommonly seen,which seriously affects the quality of life and prognosis of patients.For unresectable NELM,hepatic intra-arterial therapy is an effective option for controlling tumor progression and relieving symptoms.This therapy mainly includes transcatheter arterial embolization(TAE),transcatheter arterial chemoembolization(TACE),and selective internal radiotherapy(SIRT),and there was no significant difference in the long-term efficacy among the three therapies.Usually,TAE is recommended for patients with low-grade NELM.Conventional TACE may be considered for NELM patients who have poorly differentiated tumor or high hepatic tumor burden(HTB),and drug-eluting beads TACE is not recommended for NELM patients because it has significant hepatobiliary toxicity.SIRT can be adopted for NELM patients having portal vein thrombosis or having a history of biliary bowel surgery.In comprehensive treatment strategies for unresectable NELM,the combination use of hepatic intra-arterial interventional therapy and systemic therapy has already shown its promising prospects.Through reviewing the relevant literature,this paper summarizes the current situation and research progress of NELM.
