Summarization of the best evidence for the prevention and management of indwelling line complications in patients with hepatocellular carcinoma undergoing hepatic artery infusion chemotherapy
10.3969/j.issn.1008-794X.2025.04.016
- VernacularTitle:肝动脉灌注化疗肝癌患者留置管路并发症预防管理最佳证据总结
- Author:
Hengmei ZHU
1
;
Hongmei XIAO
;
Shuheng FANG
;
Dandan HE
;
Wenjuan FAN
;
Xiaoli ZHANG
;
Jian ZHAI
;
Jiamei YANG
Author Information
1. 200438 上海 海军军医大学第三附属医院特需诊疗科
- Keywords:
hepatic artery infusion chemotherapy;
hepatocellular carcinoma;
indwelling line complication;
evidence-based care;
summarization pf evidence
- From:
Journal of Interventional Radiology
2025;34(4):425-429
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the best evidence concerning the prevention and management of indwelling line complications in patients with hepatocellular carcinoma(HCC)receiving hepatic artery infusion chemotherapy(HAIC),and to standardize the key contents of clinical observation of complications during HAIC treatment.Methods By using the"6S"pyramid model system,the relevant literature was searched in the order from high to low.Two professionals evaluated the quality of the literature,summarized the evidence and conducted the analysis and summarization.Results Ten literature articles were finally enrolled in this study,including one article of guideline,one article of systematic review,five articles of expert consensus,one article of meta-analysis,and two articles of randomized controlled trials.Six complications(catheter displacement or falling off,catheter obstruction,unplanned extubation,arterial spasm or occlusion,infection,puncture site bleeding/local hematoma)and 22 pieces of best evidence for prevention management were summarized.Conclusion This study systematically summarizes 6 complications and their prevention and treatment in patients with HCC receiving HAIC,providing a reliable basis for clinical practice.
