Systematic evaluation of the incidence and risk factors of pulmonary infection occurring after mechanical thrombectomy for ischemic stroke
10.3969/j.issn.1008-794X.2025.04.013
- VernacularTitle:脑卒中机械取栓术后肺部感染发生率及危险因素的系统评价
- Author:
Xiaojiao YIN
1
;
Yun GAO
;
Jianxiang WANG
Author Information
1. 650000 云南昆明 昆明市第一人民医院
- Keywords:
acute ischemic stroke;
mechanical thrombectomy;
pulmonary infection;
risk factor;
systematic evaluation
- From:
Journal of Interventional Radiology
2025;34(4):407-413
- CountryChina
- Language:Chinese
-
Abstract:
Objective Using Meta-analysis to systematically evaluate the incidence and risk factors of pulmonary infection occurring in patients with acute ischemic stroke(AIS)after receiving mechanical thrombectomy.Methods A computerized retrieval of academic papers concerning the case-control study and cohort study of lung infection in patients with AIS after mechanical thrombectomy from the databases of PubMed,Web of Science,Embase,Cochrane Library,China Knowledge Network,Wanfang Data Knowledge Service Platform,and Wipro.com databases was conducted by two independent investigators.The retrieval time period was from the establishment of the database to December 2023.STAT A 16.0 software was used to make the Meta-analysis of the extracted literature.Results A total of 10 literature were included,with a combined sample size of 6 149 cases and 2 076 cases occurring lung infections.Meta-analysis revealed that the pulmonary infection in patients after mechanical thrombectomy for AIS showed a high degree of heterogeneity in the included studies(I2=97.87％,P＜0.001),and a random-effects model yielded an incidence of 31.8％for pulmonary infection.Risk factors for the occurrence of postoperative lung infection included atrial fibrillation(OR=1.33,95％CI:1.10-1.6,P=0.004),dysphagia(OR=3.83,95％CI:2.43-6.05,P＜0.001),high NIHSS score(OR=1.43,95％CI:1.05-1.94,P=0.023),impaired consciousness(OR=2.29,95％CI:1.38-3.81,P＜0.001),and intraoperative use of sedative drugs(OR=3.21,95％CI:2.91-3.54,P＜0.001).Conclusion The existing evidences indicate that patient's age ≥60 years,atrial fibrillation,dysphagia,impaired consciousness,high NIHSS score,and intraoperative use of sedative drugs are risk factors for the occurrence of pulmonary infection in AIS patients after receiving mechanical thrombectomy.In clinical practice,these risk factors should be highly valued,and these risk factors should be included in the postoperative comprehensive assessment and intervention strategies for patients so as to reduce the incidence of pulmonary infection.
