Ultrasound-guided microwave ablation versus thyroid lobectomy for benign thyroid nodules:comparison of efficacy and analysis of factors influencing prognosis
10.3969/j.issn.1008-794X.2025.04.008
- VernacularTitle:超声引导下微波消融与甲状腺腺叶切除术治疗甲状腺良性结节的效果及预后影响因素
- Author:
Peipei FAN
1
;
Chao YANG
;
Gang WANG
Author Information
1. 221000 江苏徐州 江苏市肿瘤医院超声科
- Keywords:
benign thyroid nodule;
thyroid lobectomy;
ultrasound guidance;
micro wave ablation;
prognosis
- From:
Journal of Interventional Radiology
2025;34(4):385-389
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the efficacy of ultrasound-guided microwave ablation(MWA)and thyroid lobectomy in the treatment of benign thyroid nodules,and to analyze the factors influencing prognosis.Methods A total of 146 patients with benign thyroid nodules,who received treatment at the Xuzhou Municipal Cancer Hospital of China from February 2021 to February 2022,were collected for this study.According to different treatment schemes,the patients were divided into MWA group(n=75)and surgical group(n=71).The patients of MWA group received ultrasound-guided MW A,while the patients of surgical group received thyroid lobectomy.The relevant perioperative indicators,the preoperative and postoperative thyroid functions,and the incidence of complications were compared between the two groups,and the factors influencing prognosis were analyzed.Results No statistically significant differences in the postoperative 6-month and 12-month recurrence rates existed between the two groups(both P＞0.05).The operation time,incidence of surgical scar,length of hospitalization stay,and amount of intraoperative blood loss in the MWA group were less than those in the surgical group(all P＜0.05).There were no statistically significant differences in the preoperative levels of TSH,FT3 and FT4 between the two groups(all P＞0.05).After treatment,in both groups the level of TSH was increased and the levels of FT3 and FT4 became decreased when compared with their preoperative values(all P＜0.05).However,the TSH level in the MW A group was obviously lower than that in the surgical group(P＜0.05),and FT3 and FT4 levels in the MWA group were remarkably higher than those in the surgical group(both P＜0.05).The incidence of complications in the MWA group was 2.67％,which was prominently lower than 15.49％in the surgical group(P＜0.05).Univariate analysis showed that the number of nodules,the type of nodules,the location of nodules,and the treatment scheme were the factors influencing the poor prognosis of patients with benign thyroid nodules.Multivariate logistic regression analysis revealed that the mixed type of nodule lesion and the lesion being located at risk area were the risk factors for poor prognosis of patients with benign thyroid nodules.Conclusion For the treatment of benign thyroid nodules,ultrasound-guided MWA can reduce surgical scars,shorten hospitalization stay and decrease incidence of postoperative complications with less damage on thyroid functions when compared with thyroid lobectomy.
