Progress in interventional treatment of intrahepatic cholangiocarcinoma
10.3969/j.issn.1008-794X.2025.04.002
- VernacularTitle:肝内胆管癌介入治疗研究进展
- Author:
Wei XU
1
;
Bin LIANG
Author Information
1. 430022 湖北武汉 华中科技大学同济医学院附属协和医院放射科
- Keywords:
intrahepatic cholangiocarcinoma;
local therapy;
intervention;
targeted therapy;
immunotherapy
- From:
Journal of Interventional Radiology
2025;34(4):347-354
- CountryChina
- Language:Chinese
-
Abstract:
Clinically,intrahepatic cholangiocarcinoma(iCCA)is characterized by insidious onset and strong invasiveness.The vast majority of iCCA patients have already been in the middle and advanced stage of disease when the diagnosis is confirmed,and the prognosis is poorer.The therapeutic methods for the middle and advanced iCCA mainly consist of systemic therapy and local therapy.However,the efficacy of single-agent therapies is limited.Recent studies have demonstrated that comprehensive treatment strategies based on interventional approaches,such as ablation,transarterial chemoembolization(TACE),transcatheter radioembolization(TARE),hepatic arterial infusion chemotherapy(HAIC),and iodine-125(125I)seeds implantation can significantly improve survival rate for patients with middle and advanced iCCA,meanwhile effectively reducing the incidence of adverse events.This article aims to review the latest progress in the interventional treatment for iCCA.
