Risk factors for slow-flow or no-reflow during percutaneous coronary intervention in patients with ST-segment elevation acute myocardial infarction:a meta-analysis
10.3969/j.issn.1008-794X.2025.03.004
- VernacularTitle:ST段抬高型急性心肌梗死患者经皮冠状动脉介入术中慢血流或无复流危险因素的Meta分析
- Author:
Yunfei ZHANG
1
;
Wenjuan YAN
;
Hongmei WEN
;
Weichen CHEN
;
Hongjuan ZHOU
;
Qiong HAN
;
Jiaoyang XU
;
Yingfeng LI
Author Information
1. 361004 福建厦门 厦门大学附属心血管病医院
- Keywords:
acute myocardial infarction;
percutaneous coronary intervention;
slow-flow or no-reflow;
risk factor;
meta-analysis
- From:
Journal of Interventional Radiology
2025;34(3):243-252
- CountryChina
- Language:Chinese
-
Abstract:
Objective Using meta-analysis to identify the risk factors for slow-flow or no-reflow during percutaneous coronary intervention(PCI)in patients with ST-segment elevation acute myocardial infarction(AMI).Methods A computerized retrieval of academic papers concerning the risk factors for slow-flow or no-reflow during PCI in patients with ST-segment elevation AMI from the databases of CNKI,Wanfang Database,VIP,SinoMed,PubMed,Web of Science,Embase,and Cochrane Library was conducted.The retrieval time period was from the establishment of the database to January 2024.In order to ensure the accuracy and reliability of the study,two independent reviewers screened the literature according to the preset inclusion and exclusion criteria,extracted key data,and strictly evaluated the quality of the literature.RevMan5.4 software was used to make meta-analysis.Results A total of 23 articles with a total of 9 780 cases were included in this analysis.The results of meta-analysis showed that reperfusion time ≥6 h(OR=1.52),preoperative TIMI blood flow≤level-Ⅰ(OR=1.12),heavy thrombus burden(OR=1.60),advanced age(OR=1.56),diabetes(OR=1.83),preoperative Killip grade≥Ⅲ(OR=2.52),long target vessel disease(OR=1.95),and collateral flow≤level-Ⅰ(OR=1.61)were the risk factors for slow-flow or no-reflow during PCI in patients with ST-segment elevation AMI.Preoperative systolic blood pressure＜90 mmHg(OR=1.17)and high white blood cell(WBC)count(OR=1.27)were not the risk factors for slow-flow or no-reflow during PCI in patients with ST-segment elevation AMI.Conclusion Reperfusion time ≥ 6 h,preoperative TIMI blood flow≤level-Ⅰ,heavy thrombus burden,advanced age,diabetes,preoperative Killip grade≥level-Ⅲ,long target vessel lesion,and collateral blood flow≤level-Ⅰ are the independent risk factors for slow-flow or no-reflow during PCI in patients with ST-segment elevation AMI.
