Advances in the application of optical coherence tomography in the diagnosis and treatment of intracranial atherosclerotic stenosis
10.3969/j.issn.1008-794X.2025.01.018
- VernacularTitle:光学相干断层成像在颅内动脉粥样硬化性狭窄诊疗中的应用进展
- Author:
Yuexin LU
1
;
Ming WANG
;
Shu WAN
Author Information
1. 310000 浙江杭州 浙江中医药大学第二临床医学院;浙江大学医学院附属浙江医院脑科中心
- Keywords:
intracranial atherosclerotic stenosis;
optical coherence tomography;
hemodynamics;
stroke
- From:
Journal of Interventional Radiology
2025;34(1):103-108
- CountryChina
- Language:Chinese
-
Abstract:
Intracranial atherosclerotic stenosis(ICAS)is the most prevalent etiology of ischemic stroke in the Asian population.Predicting the risk of stroke in patients with ICAS and stratifying the stroke risk can help clinicians to take early interventional measures so as to improve patient outcomes.Optical coherence tomography(OCT)is a novel ultrahigh-resolution endovascular real-time imaging technique.OCT has multiple advantages in the assessment of atherosclerotic plaque characteristics and lumen morphology,especially in the display of the fine structural features of vulnerable plaques,which provides strong image support for the assessment of the plaque stability.Combined with hemodynamic assessment,OCT can judge the formation and development trend of plaques and predict the risk of stroke recurrence in patients with ICAS,which is of great significance in guiding targeted individualized interventional therapy.This paper aims to make a comprehensive review about the recent progress in OCT technology and its integration with hemodynamic assessment for the diagnosis and treatment of ICAS,to discuss the potential application prospects of OCT in the field of cerebrovascular diseases,so as to provide a scientific basis for the risk assessment,disease monitoring,and decision-making of treatment for patients with ICAS.
