Ultrasound-guided argon-helium knife cryoablation for the treatment of advanced non-small cell lung cancer with supraclavicular lymph node metastases:a clinical observation
10.3969/j.issn.1008-794X.2024.12.008
- VernacularTitle:超声引导氩氦刀治疗晚期非小细胞肺癌合并锁骨上淋巴结转移患者的临床观察
- Author:
Zhiqiang GAO
1
;
Lei WANG
;
Jiajun TENG
;
Ping GU
;
Bo ZHANG
;
Meili MA
;
Weimin WANG
;
Chunlei SHI
;
Hua ZHONG
Author Information
1. 200030 上海 上海市胸科医院/上海交通大学医学院附属胸科医院呼吸内科
- Keywords:
argon-helium knife cryoablation;
advanced non-small cell lung cancer;
ultrasound guidance;
supraclavicular lymph node metastasis
- From:
Journal of Interventional Radiology
2024;33(12):1308-1312
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the short-term efficacy of ultrasound-guided argon-helium knife cryoablation for the treatment of advanced non-small cell lung cancer with supraclavicular lymph node metastases.Methods A total of 14 patients with advanced non-small cell lung cancer complicated by supraclavicular lymph node metastases were treated with ultrasound-guided argon-helium knife cryoablation on the basis of intravenous chemotherapy or targeted therapy.The short-term therapeutic effect and adverse reactions were analyzed.Results All the 14 patients were successfully treated with argon-helium knife cryoablation under ultrasound guidance.The overall effective rate was 78.6%,and the local compression symptoms of the patients were improved.The scores evaluated by the QLQ-C30 scale were improved when compared with preoperative values.The postoperative fever and local pain of puncture site,which were the common accompanying symptoms of argon-helium knife cryoablation,were relieved or disappeared within a few days after symptomatic treatment.Conclusion Ultrasound-guided argon-helium knife cryoablation is an effective method for local palliative treatment of advanced non-small cell lung cancer with supraclavicular lymph node metastases,which can monitor the real-time changes of lesion and evaluate the therapeutic effect in the treatment course.The clinical symptoms can be relieved within a short time after treatment,and the quality of life of patients will also be improved.