Fractional anisotrophy analysis and visualization on the reverse computing of RGB components as diffusion tensor in substantia nigra
10.16098/j.issn.0529-1356.2025.04.011
- VernacularTitle:黑质弥散张量RGB分量转化各向异性分数分析及可视化
- Author:
Yu-Qing LIU
1
;
Xiao-Jun WANG
;
Da-Feng JI
;
Hai-Hua SUN
;
Xiao-Lu XU
;
Xin-Hua ZHANG
Author Information
1. 南通大学医学院人体解剖学系,江苏南通 226001;南通大学第六附属医院(盐城市第三人民医院)影像科,江苏盐城 224000
- Keywords:
Parkinson's disease;
Substantia nigra;
Fiber;
Diffusion tensor imaging;
Visualization;
Human
- From:
Acta Anatomica Sinica
2025;56(4):459-465
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the application value of fractional anisotropy(FA)analysis of RGB component transformation in different directions of fibers in substantia nigra in Parkinson's disease(PD).Methods There were 35 cases of PD and 37 cases of normal control group.After being performed by brain diffusion tensor imaging(DTI)scanning,the sequence was imported into 3DSlicense 5.6.0,and the diffusion module was used to implement pseudo color mapping based on FA,locate and segment substantia nigra,and use the substantia nigra mask as the tracking starting point.After forming tracing,fibers were imported into DTIANALYSIS 1.51,converting the RGB components into FA values for analysis,and visualized the analysis result.At the same time,fiber length,fiber density,and segmented FA point cloud percentage were compared.Results Compared with the normal group,the length of substantia nigra fibers in the PD group was shorter[(95.14±19.85)mm vs(115.99±21.39)mm,P＜0.01],and there was a statistical difference between the two groups.There was no statistical difference in fiber density[(0.07±0.05)/mm3 vs(0.10±0.12)/mm3,P＞0.05]between control group and PD group.The percentage of FA segment point clouds in the PD group was lower than that in the normal group at 0.9-1,but the principal component characteristics of the point cloud ratios in each FA segment were not significant.Conclusion Based on the transformation of RGB components into FA analysis,the length,density,and FA values of substantia nigra nerve fibers in PD patients can be quantified and visualized,providing a basis for the study of PD neural pathways.
