Zeolite-based hemostatic materials:current status,challenges and future prospects
10.11855/j.issn.0577-7402.0841.2025.0829
- VernacularTitle:沸石基止血材料:现状、挑战与未来展望
- Author:
Ni ZHU
1
;
Tan-Shi LI
Author Information
1. 南开大学医学院,天津 300701;解放军总医院第一医学中心普通外科,北京 100853
- Keywords:
trauma;
hemostatic materials;
zeolite
- From:
Medical Journal of Chinese People's Liberation Army
2025;50(10):1219-1225
- CountryChina
- Language:Chinese
-
Abstract:
Shock and death resulting from traumatic massive hemorrhage have become the leading cause of trauma-related mortality,accounting for over 70%of deaths within 24 hours.Therefore,achieving rapid hemostasis to reduce multiple organ failure caused by excessive blood loss and then improving survival rates has become a critical challenge in trauma care.Common local hemostatic materials for trauma can be categorized by their properties into organic and inorganic materials,or by their mechanism of action into three types:physical adsorbents,biologically active agents,and adhesive sealants.This review summarizes the characteristics and drawbacks of typical representatives from these three categories.It then focuses on discussing the application of zeolite materials in hemostasis,specifically three forms:zeolite particles,zeolite-polymer composites,and bio-based zeolite materials.Furthermore,the latest research progress in the fundamental theory and practical applications of zeolite-based hemostatic materials are reviewed,aiming to provide new insights for future research on zeolite in hemostasis.
