Research progress in Chikungunya fever
10.11855/j.issn.0577-7402.1764.2025.0902
- VernacularTitle:基孔肯雅热研究进展
- Author:
Guan-Zhen WANG
1
;
Xiao-Xi LI
;
Yan LIU
;
Lei HUANG
Author Information
1. 解放军总医院第五医学中心感染病医学部感染性疾病科/国家感染性疾病临床医学研究中心,北京 100039
- Keywords:
Chikungunya fever;
epidemiology;
pathogenic mechanisms;
immunology;
diagnosis;
vaccine
- From:
Medical Journal of Chinese People's Liberation Army
2025;50(9):1070-1075
- CountryChina
- Language:Chinese
-
Abstract:
Chikungunya fever(CHIKF)is a mosquito-borne infectious disease caused by Chikungunya virus(CHIKV)infection,which has become a significant public health threat of global concern in recent years.The acute phase of CHIKF is primarily characterized by sudden high fever,severe polyarthralgia,and rash.The disabling arthralgia may progress to chronic arthritis,with symptoms lasting for months or even years.This not only severely reduces patients'quality of life and impairs their labor capacity,but also imposes a heavy socioeconomic burden.In recent years,significant progress has been made in CHIKF-related research.This review elaborates on the latest research achievements in the fields of the disease's epidemiology,clinical manifestations,pathogenic mechanisms,immune response,diagnostic techniques,and prevention and treatment strategies,aiming to provide comprehensive and in-depth references for researchers and clinicians in relevant fields.
