Research progress of the role of cholecystokinin in regulating learning and memory in central nervous system

VernacularTitle:中枢神经系统胆囊收缩素调控学习记忆功能的研究进展
Author: Ya-Yuan LU ¹ ; Lei CHEN ; Rui DONG
Author Information

1. 解放军联勤保障部队第904医院常州医疗区麻醉科,江苏常州 213000
Keywords: cholecystokinin; learning and memory; central nervous system; synapses
From: Medical Journal of Chinese People's Liberation Army 2025;50(7):897-904
CountryChina
Language:Chinese
Abstract: Learning and memory are basic and important advanced functions of the brain,and have always been a hot and difficult research area in neuroscience.Despite the significant progress in research on learning and memory,the mechanism is still not fully clear.Cholecystokinin(CCK),an early identified brain gut peptide,is widely distributed and involved in regulating a variety of functions in the central nervous system.In recent years,numerous studies have shown that CCK plays an important role in the regulation of learning and memory by affecting the function of neurons and glial cells.This article reviews the role and mechanism of CCK in learning and memory,to provide a theoretical basis for the development of CCK-related drugs and their applications.