Research progress on the relationship between fungal infection and multiple sclerosis
10.11855/j.issn.0577-7402.1174.2025.0325
- VernacularTitle:真菌感染与多发性硬化的关系研究进展
- Author:
Ya-Ling HE
1
;
Rong YIN
Author Information
1. 甘肃省中心医院神经内科,甘肃 兰州 730030
- Keywords:
multiple sclerosis;
fungi infection;
pathogenesis
- From:
Medical Journal of Chinese People's Liberation Army
2025;50(6):767-770
- CountryChina
- Language:Chinese
-
Abstract:
Multiple sclerosis(MS)is a demyelinating disease of the central nervous system associated with autoimmunity.Its main pathological characteristics involve glial hyperplasia,demyelination and axonal damage accompanied by inflammatory infiltration of the central nervous system.Currently,it is believed that MS is related to multiple factors such as genetic susceptibility,environment,infection,lifestyle,and immunity.However,its exact etiology remains unclear.In recent years,studies have shown that both MS patients and experimental autoimmune encephalomyelitis animal models are closely associated with fungal infection.This review summarizes the research progress on the correlation between fungal infection and MS,and the role of fungi in the pathogenesis of MS,aiming to provide new insights for exploring the pathogenesis,clinical diagnosis and treatment of MS.
