Research progress in the pathogenesis of preeclampsia
10.11855/j.issn.0577-7402.0891.2024.1225
- VernacularTitle:子痫前期发病机制研究进展
- Author:
Jie HUANG
1
;
Jian HAN
;
Jian-Xin GUO
;
Ge DIAO
;
Li LI
Author Information
1. 陆军军医大学大坪医院妇产科,重庆 400042
- Keywords:
preeclampsia;
pathogenesis;
animal model;
in vitro model
- From:
Medical Journal of Chinese People's Liberation Army
2025;50(3):351-357
- CountryChina
- Language:Chinese
-
Abstract:
Preeclampsia(PE)is a severe hypertensive disorder during pregnancy that seriously affects the health of pregnant women and fetuses.Currently,the treatment is merely symptomatic,with unsatisfactory efficacy and often resulting in an increased incidence of therapeutic preterm birth.An increasing number of studies on PE suggest that the"unitary"theory is no longer adequate to elucidate its pathogenesis.PE is regarded as a syndrome influenced by multiple factors,featuring a complex pathogenesis and the potential to affect multiple organs and systems.This review summarizes the latest advancements in the classification,etiology,pathogenesis,and research models(including animal and in vitro models)of PE,aiming to provide references for subsequent research and offer assistance in clinical prevention,screening,and treatment.
