Role of macrophage extracellular traps in inflammatory diseases
10.16352/j.issn.1001-6325.2025.10.1368
- VernacularTitle:巨噬细胞胞外诱捕网在炎性疾病中的作用
- Author:
Qianqian WU
1
;
Kaiting MA
;
Lingfei CAO
;
Xiaoping WANG
Author Information
1. 新乡医学院 基础医学院,河南 新乡 453000
- Keywords:
macrophage;
macrophage extracellular traps;
inflammatory disease
- From:
Basic & Clinical Medicine
2025;45(10):1368-1371
- CountryChina
- Language:Chinese
-
Abstract:
Macrophage extracellular traps(METs)are extracellular fibrous web-like structures produced by macro-phages.Under physiological conditions,METs capture and kill microorganisms by releasing high concentrations of granular proteins,serving as an innate immune defense mechanism and playing a vital protective role in resisting the progression of inflammatory diseases.Excessive release of METs can also exacerbate the inflammatory response and cause further tissue damage.