Single-center retrospective analysis of peritoneal mesothelioma
10.16352/j.issn.1001-6325.2025.10.1362
- VernacularTitle:腹膜间皮瘤单中心回顾性分析
- Author:
Qi LIU
1
;
Muwen NIE
;
Jingqi ZHANG
;
Ningning LI
;
Lin ZHAO
Author Information
1. 中国医学科学院 北京协和医学院 北京协和医院 肿瘤内科,北京 100730
- Keywords:
peritoneal mesothelioma;
cytoreductive surgery;
peritoneal heat infusion chemotherapy;
chemotherapy
- From:
Basic & Clinical Medicine
2025;45(10):1362-1367
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnosis and treatment experience of malignant peritoneal mesothelioma by analyzing the clinical characteristics of patients with single center peritoneal mesothelioma.Methods Retrospec-tively analyze the clinical data,including age and treatment regimens,of 99 patients with malignant peritoneal mes-othelioma admitted to Peking Union Medical College Hospital from June 2012 to July 2023.Kaplan-Meier for surviv-al analysis and Logistic and Cox regression were applied to assess the impact of factors like age and treatment regi-mens on survival time.Results The median age of diagnosis for 99 patients with peritoneal mesothelioma was 56 years,of which 82 were pathologically diagnosed.Among them,38 cases(51.4%)underwent tumor cell reduction surgery,and 57 cases(77.0%)underwent systemic or local treatment.The median survival time for all patients was 43 years.The age of diagnosis may affect the prognosis of patients with malignant mesothelioma,and those aged≥65 at the time of diagnosis have a worse prognosis.Conclusions Malignant peritoneal mesothelioma is a rare but invasive malignant tumor with a poor prognosis.There is still a need to develop novo drugs and comprehensive treat-ment strategies.
