Molecular mechanisms of selenium binding protein 1 expression regulation in cancer cells
10.16352/j.issn.1001-6325.2025.09.1224
- VernacularTitle:硒结合蛋白1在癌细胞中表达调控的分子机制
- Author:
Lei KANG
1
;
Junlan ZHU
Author Information
1. 宁波大学 医学部,浙江 宁波 315211;宁波市北仑区人民医院 精准医学研究中心,浙江 宁波 315800;宁波市北仑区疾病预防控制中心 检验科 浙江 宁波 315899
- Keywords:
selenium binding protein 1;
cancer cell;
molecular regulation;
targeted therapy
- From:
Basic & Clinical Medicine
2025;45(9):1224-1228
- CountryChina
- Language:Chinese
-
Abstract:
Selenium binding protein 1(SELENBP1)is a protein related to selenium metabolism.Studies have found that SELENBP1 is abnormally expressed in various cancer cells,and its expression level is closely related to tumor occurrence,development,metastasis,and prognosis.Therefore,SELENBP1 is widely concerned,and its role in bladder cancer is being studied in-depth.This article mainly summarizes the expression regulation,biological functions,and potential molecular pathways of SELENBP1 in thyroid cancer,colorectal cancer,non-small cell lung cancer,prostate cancer,oral squamous cell cancer,and bladder cancer.The research results may provide a reference for understanding the mechanisms of SELENBP1 in cancer cells and offer new ideas and targets for tumor diagnosis and prevention.
