Expression of Slitrk6 during testicular tissue development in rats
10.16352/j.issn.1001-6325.2025.07.0912
- VernacularTitle:大鼠睾丸组织发育过程中Slitrk6的表达
- Author:
Shanshan LIU
1
;
Jie BAI
;
Xueying WANG
;
Lin GAO
;
Yan ZHANG
;
Taodi LIU
;
Xinlai ZHANG
Author Information
1. 内蒙古医科大学 基础医学院 医学神经生物学实验室,内蒙古 呼和浩特 010110
- Keywords:
male infertility;
testicular tissue;
Slitrk6;
spermogenesis
- From:
Basic & Clinical Medicine
2025;45(7):912-917
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the transcriptional and translational expression of Slitrk6 in rat spermatogene-sis.Methods The mRNA transcription level and translation level of Slitrk6 were detected by RT-qPCR and West-ern blot,respectively in testis of rats aged 2-65 days(repeat three times at each time point).Results The mRNA expression of Slitrk6 reached the highest on day 4 and day 10.SLITRK6 protein was continuously expressed during testis development in rats.Slitrk6 was found in human testis through PPI network.Conclusions Slitrk6 is potential-ly involved in mitosis and meiosis in spermatogenesis;The Slitrk6 may be one of the key genes in spermatogenesis.SLITRK6 protein is involved in mitosis and the transformation of round spermatids.The results lay a foundation for subsequent research on male infertility.
