Disease-associated gut microbiota involvement and its mechanisms in the lung injury
10.16352/j.issn.1001-6325.2025.05.0681
- VernacularTitle:疾病相关的肠道菌群微生态在肺损伤形成的机制研究
- Author:
Qianmei ZHU
1
;
Qingyang LI
;
Lu CHE
;
Yuguang HUANG
Author Information
1. 中国医学科学院北京协和医学院北京协和医院麻醉科,北京 100730
- Keywords:
gut microbiota;
lung injury;
immunity;
perioperative
- From:
Basic & Clinical Medicine
2025;45(5):681-685
- CountryChina
- Language:Chinese
-
Abstract:
The gut microbiota is generally thought in regulating the body's metabolism and immune function.The imbalance of gut microbiota is related to the occurrence and development mechanisms of acute and chronic lung dis-eases,resulting from lung injury.The"gut-lung axis"pays a main role in various ways in the occurrence of lung injury,including intestinal barrier dysfunction,reduced diversity of gut microbiota,decreased secretion of beneficial metabolites,translocation of gut microbiota and metabolites to the lungs,immune damage to the body and lungs,increased inflammatory response in the lungs.
